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CD BioSciences offers a unique range of high-end custom fluorescence microscopes, small animal imaging devices, and fluorescent probes to perform fluorescence-based measurements in a variety of spatial (nm to cm), and temporal (ns). Our laboratories offer consultancy services and support the application of novel spectroscopic methods and advanced microscopy techniques to achieve high spatial and temporal resolution nanotechnology from whole in vivo animal imaging to sub 70 nm imaging using super-resolution. In addition to using state-of-the-art specialist instrumentation, we train researchers in the use of advanced imaging techniques that are used to study macromolecules, and cell dynamics and characterize biological materials with nanometric precision.
The new instrument especially addresses the needs of those microtome users who prefer manual over motorized sectioning. During the development of the RM2235, special emphasis was placed on translating the known user requirements for sturdy manual microtomes in the best possible way. User safety and reliable performance were also the focus of further improvement. The housing of the instrument has been adapted to modern user requirements for improved ergonomics. Control elements that are used several times a day are positioned for optimum user friendliness and are very simple to operate. The Leica RM2235 comes standard with an ergonomically integrated, spacious section waste tray. Optional arm rests make daily work easier providing considerably enhanced user comfort, especially for routine applications. Safety features such as two independent handwheel locking systems and an optimized knife guard integrated into the knife holder set new standards.
1. Fluorescence imaging at all length scales: from single-molecule detection to in vivo small animal imaging.
The field of optical microscopy imaging is experiencing major technical advances which are allowing cell biologists and physicians to visualize a new, dynamic, sub-cellular world where genes and gene products interact in space and time, in health and disease with nanometer-accuracy.
2. Micro-and nano-scale imaging.
The facility currently provides: wide-field fluorescence imaging microscopy, stereo microscopy, iterative deconvolution and computationally derived optical sectioning, confocal one-photon and two-photon laser scanning confocal microscopy imaging, Fluorescence Correlation Spectroscopy (FCS), Fluorescence Resonance Energy Transfer (FRET), Fluorescence Lifetime Imaging (FLIM), time-correlated-single-photon-counting (TCSPC), near-infrared (NIR) imaging, and a super-resolution Stimulated Emission Depletion (STED) confocal microscope for probing biological and artif
Main Use: Fast confocal scanning of live or fast moving specimens
The Leica RM2235 is a manual high-performance microtome with mechanical precision specimen feed, designed above all for the manual sectioning of biological specimens embedded in paraffin.
CD BioSciences offers Leica RM2235 Rotary Microtome-based imaging and analysis services to researchers from all over the world. Our solutions will fully meet your experimental needs. We sincerely look forward to establishing a partnership with you. If you have any questions, please contact us directly.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.