Imaging and Analysis Services—Leica M205 FA Fluorescence Stereomicroscope

CD BioSciences offers a unique range of high-end custom fluorescence microscopes, small animal imaging devices, and fluorescent probes to perform fluorescence-based measurements in a variety of spatial (nm to cm), and temporal (ns). Our laboratories offer consultancy services and support the application of novel spectroscopic methods and advanced microscopy techniques to achieve high spatial and temporal resolution nanotechnology from whole in vivo animal imaging to sub 70 nm imaging using super-resolution. In addition to using state-of-the-art specialist instrumentation, we train researchers in the use of advanced imaging techniques that are used to study macromolecules, and cell dynamics and characterize biological materials with nanometric precision.

Name of the Instrument/Platform

Leica M205 FA Fluorescence Stereomicroscope

MANUFACTURER:

Leica

MODEL:

M205

Introduction

Fluorescence microscopy techniques are critical for studying the functions within organisms in modern developmental, molecular, and cellular biology. Fluorescence microscopy gives researchers insight into a world normally hidden from sight. The structures within an organism and their dynamic processes can be specifically targeted with fluorescence dyes to render them visible at the sub cellular level, which helps researchers to better understand the molecular principles and complex relationships on which life itself is based.

Feature Highlights

1. Get highly reliable and publishable results as all parameters are always auto-stored for you.
2. Eliminate interruption in your workflow with the four position coded filter changer.
3. Add a footswitch for easy change of filters, focus, and illumination adjustment, keeping both hands free for screening.

Applications

1. Fluorescence imaging at all length scales: from single-molecule detection to in vivo small animal imaging.
The field of optical microscopy imaging is experiencing major technical advances which are allowing cell biologists and physicians to visualize a new, dynamic, sub-cellular world where genes and gene products interact in space and time, in health and disease with nanometer-accuracy.
2. Micro-and nano-scale imaging.
The facility currently provides: wide-field fluorescence imaging microscopy, stereo microscopy, iterative deconvolution and computationally derived optical sectioning, confocal one-photon and two-photon laser scanning confocal microscopy imaging, Fluorescence Correlation Spectroscopy (FCS), Fluorescence Resonance Energy Transfer (FRET), Fluorescence Lifetime Imaging (FLIM), time-correlated-single-photon-counting (TCSPC), near-infrared (NIR) imaging, and a super-resolution Stimulated Emission Depletion (STED) confocal microscope for probing biological and artif

Summary

Main Use: Fluorescence imaging
The Leica M205 FA stereomicroscopes features Leica Microsystems' patented technology. The principle refers to the microscope's third beam path, reserved exclusively for fluorescence illumination to deliver evenly illuminated, reflex-free fields of view at all zoom settings. This separation of illumination and observation beam paths ensures brilliant fluorescence images, rich in detail and contrast, with the best light efficiency. Even weak fluorescence signals are displayed with remarkable image quality

CD BioSciences offers Leica M205 FA Fluorescence Stereomicroscope-based imaging and analysis services to researchers from all over the world. Our solutions will fully meet your experimental needs. We sincerely look forward to establishing a partnership with you. If you have any questions, please contact us directly.

For research use only, not intended for any clinical use.

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