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Imaging and Analysis Services—Leica Deep In Vivo Explorer SP8 DIVE

CD BioSciences offers a unique range of high-end custom fluorescence microscopes, small animal imaging devices, and fluorescent probes to perform fluorescence-based measurements in a variety of spatial (nm to cm), and temporal (ns). Our laboratories offer consultancy services and support the application of novel spectroscopic methods and advanced microscopy techniques to achieve high spatial and temporal resolution nanotechnology from whole in vivo animal imaging to sub 70 nm imaging using super-resolution. In addition to using state-of-the-art specialist instrumentation, we train researchers in the use of advanced imaging techniques that are used to study macromolecules, and cell dynamics and characterize biological materials with nanometric precision.

Name of the Instrument/Platform

Leica Deep In Vivo Explorer SP8 DIVE

MANUFACTURER:
Leica

Introduction

The SP8 DIVE provides spectral freedom. Equipped with 4Tune, a tunable, non-descanned detection system, the SP8 DIVE offers you unlimited flexibility and enables you to develop new multicolor deep in vivo experiments.
The SP8 DIVE provides maximum penetration depth. The new Vario Beam Expander can be tuned for improved penetration depth depending on the animal model. Capture twice as much of the fluorescence signal with the 4Tune detection. Achieve more contrast and depth for multicolor, deep in vivo imaging.

Applications

1. Fluorescence imaging at all length scales: from single-molecule detection to in vivo small animal imaging.
The field of optical microscopy imaging is experiencing major technical advances which are allowing cell biologists and physicians to visualize a new, dynamic, sub-cellular world where genes and gene products interact in space and time, in health and disease with nanometer-accuracy.
2. Micro-and nano-scale imaging.
The facility currently provides: wide-field fluorescence imaging microscopy, stereo microscopy, iterative deconvolution and computationally derived optical sectioning, confocal one-photon and two-photon laser scanning confocal microscopy imaging, Fluorescence Correlation Spectroscopy (FCS), Fluorescence Resonance Energy Transfer (FRET), Fluorescence Lifetime Imaging (FLIM), time-correlated-single-photon-counting (TCSPC), near-infrared (NIR) imaging, and a super-resolution Stimulated Emission Depletion (STED) confocal microscope for probing biological and artif

Summary

The SP8 DIVE Deep In Vivo Explorer is the first spectrally tunable solution for multicolor, multiphoton (MP) imaging.

CD BioSciences offers Leica Deep In Vivo Explorer SP8 DIVE-based imaging and analysis services to researchers from all over the world. Our solutions will fully meet your experimental needs. We sincerely look forward to establishing a partnership with you. If you have any questions, please contact us directly.

For research use only, not intended for any clinical use.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.

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