Email:
Tel: 
CD BioSciences offers a unique range of high-end custom fluorescence microscopes, small animal imaging devices, and fluorescent probes to perform fluorescence-based measurements in a variety of spatial (nm to cm), and temporal (ns). Our laboratories offer consultancy services and support the application of novel spectroscopic methods and advanced microscopy techniques to achieve high spatial and temporal resolution nanotechnology from whole in vivo animal imaging to sub 70 nm imaging using super-resolution. In addition to using state-of-the-art specialist instrumentation, we train researchers in the use of advanced imaging techniques that are used to study macromolecules, and cell dynamics and characterize biological materials with nanometric precision.
Imaging requires light, but too much light can damage your cells. Light sheet microscopy is the most gentle imaging method to date, as it reduces the overall photodamage from phototoxicity and bleaching. This automatically increases the viability of your specimen. Particularly developmental biology benefits from light sheet imaging: The combination of low light illumination and high speed acquisition allows you to follow sensitive developing organisms like a Drosophila embryo over long time periods and to understand how tissue and organs form in real time and 3D.
Light sheet microscopy is a highly suitable way of imaging sensitive samples or fast biological processes by illuminating the specimen only in a single plane. Since there is no out-of-focus excitation, phototoxic effects can be reduced to the focal plane. It also means that you automatically have optical sectioning and you can image specimens in 3D by moving the sample through the light sheet.
1. Fluorescence imaging at all length scales: from single-molecule detection to in vivo small animal imaging.
The field of optical microscopy imaging is experiencing major technical advances which are allowing cell biologists and physicians to visualize a new, dynamic, sub-cellular world where genes and gene products interact in space and time, in health and disease with nanometer-accuracy.
2. Micro-and nano-scale imaging.
The facility currently provides: wide-field fluorescence imaging microscopy, stereo microscopy, iterative deconvolution and computationally derived optical sectioning, confocal one-photon and two-photon laser scanning confocal microscopy imaging, Fluorescence Correlation Spectroscopy (FCS), Fluorescence Resonance Energy Transfer (FRET), Fluorescence Lifetime Imaging (FLIM), time-correlated-single-photon-counting (TCSPC), near-infrared (NIR) imaging, and a super-resolution Stimulated Emission Depletion (STED) confocal microscope for probing biological and artif
Light sheet microscopy usually requires a dedicated optical setup on an independent system, where the illuminating and detecting objective are perpendicular to each other. The Leica TCS SP8 DLS makes light sheet microscopy as easy as never before. The unique TwinFlect mirror device deflects the illuminating light sheet at a 90° angle and allows the integration of the illumination and detection beam path into the vertical axis of every inverted Leica TCS SP8 without compromising confocal functionality.
CD BioSciences offers Leica TCS SP8 Digital Light Sheet Microscope-based imaging and analysis services to researchers from all over the world. Our solutions will fully meet your experimental needs. We sincerely look forward to establishing a partnership with you. If you have any questions, please contact us directly.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.