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The characterization of molecules is an important part of the process, enabling the physical and chemical properties of molecules to be resolved. CD BioSciences has excellent analytical staff, years of analytical experience, and cutting-edge instrumentation. Using LC-MS, multiple HPLC, and other techniques, we can accurately quantify/characterize the DAR of coupled drugs, residual small molecules, endotoxins, and more.
The Reichert4SPR 4-Channel Surface Plasmon Resonance system allows users to accelerate and enhance the drug discovery process in the following ways:
-Easy set-up and streamlined workflow.
-Utmost sensitivity and maximum uptime.
-Robust fluid handling system to run demanding assays.
Immobilization Techniques:
1. Amine coupling to carboxylated planar monolayer or branched dextran sensor chips.
2. Thiol coupling using a native or introduced cysteine.
3. NeutrAvidin, streptavidin, or avidin capture of biotinylated molecules.
4. Nickel NTA capture of histidine-tagged molecules.
5. Protein A capture of antibodies.
6. Lipid monolayer formation on a hydrophobic surface.
The Reichert 4 SPR system is a four channel surface plasmon resonance spectrometer for label-free measurement of macromolecular association and dissociation kinetics. SPR is suitable for a wide range of interactants including proteins, nucleic acids, lipids, carbohydrates, small drugs and synthetic polymers and nanoparticles.
CD BioSciences offers its customers Surface Plasmon Resonance-based molecular characterization services that contribute to the process and drug development process of biomolecules. If you need our technical support, please contact us directly.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.