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The characterization of molecules is an important part of the process, enabling the physical and chemical properties of molecules to be resolved. CD BioSciences has excellent analytical staff, years of analytical experience, and cutting-edge instrumentation. Using LC-MS, multiple HPLC, and other techniques, we can accurately quantify/characterize the DAR of coupled drugs, residual small molecules, endotoxins, and more.
Simple dip and read measurements can be used to identify the presence of a molecule in a solution, while time-course analysis allows for measurements of binding affinities. A wide range of probes are available (standard antibodies, Protein A, Ni-NTA, Streptavidin, etc.) making this system extremely flexible in application; furthermore, limited custom probe production is possible in coordination with the manufacturer.
Bio-layer interferometry uses the interference produced from two light reflections of a single source to measure the aggregation of a target molecule on the sensor surface: as the target molecules aggregate or dissociate from the probe surface, the distance of between the reflections sources change accordingly.
CD BioSciences offers its customers Biolayer Interferometer (BLITZ)-based molecular characterization services that contribute to the process and drug development process of biomolecules. If you need our technical support, please contact us directly.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.