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The characterization of molecules is an important part of the process, enabling the physical and chemical properties of molecules to be resolved. CD BioSciences has excellent analytical staff, years of analytical experience, and cutting-edge instrumentation. Using LC-MS, multiple HPLC, and other techniques, we can accurately quantify/characterize the DAR of coupled drugs, residual small molecules, endotoxins, and more.
Bruker micrOTOF - Agilent 1260 HPLC. The Bruker micrOTOF ESI instrument with a time-of-flight (TOF) detector (shared instrument resource) can be interfaced directly t the Agilent 1260 HPLC system which can deliver solvent flow rates between 50 microliters and 5000 microliters per minute, appropriate for standard analytical HPLC analyses as well as rapid high-performance HPLC prot℃ols. The micrOTOF-HPLC configured system is regularly used for evaluating recombinant protein masses (SEC), providing accurate mass for organic synthesis products undergoing NMR analysis, and identification/validation of known metabolites.
Bruker InsightMR software and 5 mm flow probe/pump unit (4m) with chiller/heater bath for on-line kinetic/reaction monitoring by NMR analysis. Working temperature range -20℃ to +200℃. Working flow rate ranges 0.001-10ml/min. The Bruker InsightMR package allows for real-time reaction monitoring by NMR analysis.
CD BioSciences offers its customers Bruker InsightMR Software-based molecular characterization services that contribute to the process and drug development process of biomolecules. If you need our technical support, please contact us directly.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.