Confocal Microscope Imaging Service—M33-LSM 880 Axio Observer (Inverted) with Airyscan/Airyscan Fast and Incubation and 40×/1.2 W, Glycerol AutoCorr Objective

Confocal microscopy is an optical imaging technique that uses point-by-point illumination and spatial pinhole modulation to remove scattered light from the non-focal plane of the sample, allowing for improved optical resolution and visual contrast compared to traditional imaging methods. CD BioSciences, the imaging experts, can provide you with M33-LSM 880 Axio Observer (Inverted) with Airyscan/Airyscan Fast and Incubation and 40×/1.2 W, Glycerol AutoCorr Objective-based confocal microscopy imaging services.

Name of the Instrument/Platform

M33-LSM 880 Axio Observer (Inverted) with Airyscan/Airyscan Fast and Incubation and 40×/1.2 W, Glycerol AutoCorr Objective

Introduction

1. Widefield Illumination
1) LED
2) LED for brightfield
2. Lasers for Confocal Imaging
1) Laser Diode 405 25mW
2) Argon 458, 488, 514 30mW
3) DPSS 561 15mW
4) HeNe 594 2mW
5) HeNe 633 5mW
3. Filter
1) CH1: 371-735
2) CH₂: 479-735
3) CH3 Quasar (GaAsP) : 416-696 in 8.3 nm steps
4) CHD: T-PMT (transmitted light)
5) AIRYSCAN: BP 420-480+BP495-550; BP 420-480+BP495-620; BP 420-480+LP605; BP 465-505+LP525; BP 495-550+LP570; BP 570-620+LP645
4. Objectives
1) 10×/0.45 plan-apochromat
2) 20/0.8 plan-apochromat
3) 40×/1.3 EC plan-apochromat Oil DIC
4) 40×/1.2 LD LCI plan-apochromat, Water, Glycerol DIC AutoCorr
5) 63×/1.4 plan-apochromat Oil DIC
5. Additional Devices
1) Incubation with CO₂
2) XY Motorized Stage
3) Piezo Z stage insert
4) Multiple Position Acquisition
5) High Dynamic Range acquisition (HDR)
6) FRAP
7) Tiles

Summary

The M33 system is an inverted point laser scanning confocal microscope (LSM880).It is a complete spectral system allowing the free choice of detection and the acquisition of lambda-stacks as well as subsequent unmixing for the separation of dyes with overlapping emission spectra. LSM880 features a highly sensitive array of 32 GaAsP (Gallium Arsenide) detectors with a QE of 45% and up to 2× SNR as compared to standards PMTs.
The system is equipped with a motorized xyz-stage and a definite focus (hardware autofocus device). The system is fully programmable and therefore able to run multidimensional experiments including any combination of the following: multiple positions, multiple wavelengths, z-Stacks, time-lapse.
In addition the M33 system features Airyscan - a hexagonal GaSaP detector. This device enables improvement of the resolving power in XYZ by a factor of 1.7. The Airyscan fast option allows 4× faster acquisition with up to 1.5× improvement of the optical resolving power and 4

CD BioSciences' M33-LSM 880 Axio Observer (Inverted) with Airyscan/Airyscan Fast and Incubation and 40×/1.2 W, Glycerol AutoCorr Objective-based confocal microscopy service is an ideal partner for cutting-edge biomedical research, providing precise 3D imaging, as well as accurate imaging of cell structure and dynamic processes, all in one package. If you are interested, please feel free to contact us.

For research use only, not intended for any clinical use.

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