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CD BioSciences' chemical and biomolecular analysis laboratories have a wide range of instruments including high-field nuclear magnetic resonance (NMR), liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS), high-performance liquid chromatography (HPLC) and more. Based on these instruments, we can monitor chemical reactions and protein stability, determine molecular structures, obtain purity (including trace metal content), or study other properties of various materials.
1. Protein folding
2. Ionization state
3. Solution structure
4. Molecular dynamics
5. Protein hydration
6. Hydrogen bonding
7. Metabolite analysis
8. Chemical analysis
9. Material science
10. Drug screening and design
11. Native membrane protein
12. Weak intermolecular interactions
The Nuclear Magnetic Resonance (NMR) instruments can provide structure or molecular interaction analysis of small organic molecules, peptides, 3D structure of proteins up to 12-15 kDa, ligand binding to larger proteins, lipids, carbohydrates, nucleic acids of 8 kDa or less, and selected metals.
The 500 MHz NMR instrument has different probes allowing multiple configurations while the 300 MHz NMR is limited to proton, carbon, and fluorine studies.
Default hardware includes a Prodigy Cryoprobe (Inverse probe) for high sensitivity proton, carbon, nitrogen, and fluorine studies of samples in liquid solution. Available hardware includes a High Resolution Magic Angle Spinning probe for lipids, cells, polymers, or high viscosity samples and a Broad Band (Direct probe) for a wide range of nuclei.
If you are interested in Nuclear Magnetic Resonance (NMR)-based chemical and biomolecular analysis services, please do not hesitate to contact us.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.