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Biomedical Imaging Service—Akoya Biosciences Vectra Polaris Whole Slide Imaging System

Biomedical imaging usually refers to the science of researching image composition, capture and storage technology, and the research and development of instruments and equipment. CD BioSciences has a variety of imaging equipment, which can visually describe and accurately measure the structure and function of living organisms across scales, provide imaging omics research methods for complex life science problems and major diseases, and facilitate panoramic research and analysis of biomedical science.

Name of the Instrument/Platform

Akoya Biosciences Vectra Polaris Whole Slide Imaging System

Introduction

Akoya Biosciences Vectra Polaris Specifications
1. Slide Capacity: 80+ (continuous loading)
2. Output File Format: .qptiff and .im3
3. Objectives: 5, 10, 20, 40×
4. Image Acquisition: Brightfield and 9-channel fluorescence-30 minutes to an hour
5. InFORM Image Analysis Features: Tissue segmentation (machine learning), cell segmentation, phenotyping (machine learning), scoring, spatial analysis
6. Scan Method: Tile
7. Z-Stacking: No
8. Liquid Crystal Tunable Filter: Yes
9. Continuous Workflow: Yes
10. Multispectral Imaging with Unmixing: Yes
11. Integrated Spectral Unmixing: Yes
12. Autofluorescence Removal Yes: Quantitation and isolation using automatically selected AF filter
13. Synthetic Spectra for Unmixing: Yes
14. Multiband Epi-Fluorescence Filters: Yes
15. Flash LEDs for Photobleaching Protection: Yes
16. Local Support Team: Sales Specialist/Application Scientists (PhD)/Service Engineer (PhD)/Bioinformatics Scientist (PhD)

Summary

The Vectra Polaris Quantitative Pathology Imaging System is good for high throughput whole slide image acquisition of both brightfield and high-plex fluorescent images-up to 6 colors plus DAPI using the rapid acquisition MoTIF workflow. Although Opal TSA conjugated dyes are recommended, a broad spectrum of fluorophores are compatible with the systems filter sets. Both 200× and 400× total magnification are available, with the latter recommended for ISH analysis that demands higher resolution. Importantly, this system affords increased analytical sensitivity/enhanced signal to noise ratios compared to alternative slide scanners afforded through multispectral unmixing and removal of autofluorescence signals. Furthermore, the system is integrated with a quantitative image analysis pipeline (inForm) that affords generation of continuous pathomics datasets to empower discovery including tissue classification, positive pixel analysis, spatial analysis, and phenotyping.

CD BioSciences offers you biomedical imaging solutions based on Akoya Biosciences Vectra Polaris Whole Slide Imaging System. We look forward to being your research partner. Please do not hesitate to contact us if you need us.

For research use only, not intended for any clinical use.
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