Tissue Imaging Service—Leica SP8 Intravital Multiphoton/Confocal System

Depth imaging in tissue is one of the greatest challenges facing optical microscopists. As the depth into the sample progressively increases, scattering and various optical aberrations gradually deteriorate, ultimately placing a practical limit on the possible imaging depths. CD BioSciences can solve your challenges with our advanced equipment and we offer Leica SP8 Intravital Multiphoton/Confocal System-based tissue imaging services.

Name of the Instrument/Platform

Leica SP8 Intravital Multiphoton/Confocal System

MANUFACTURER:

Leica

Introduction

System Specifications
• Microscope (Upright DM6000 CFS stand)
1. DM6000 CFS with motorized focus drive for transmitted light, epifluorescence and confocal laser scanning microscopy
2. Motorized Moveable Base Plate - Scientifica stage for ample space for the sample
3. 2 position motorized nosepiece
4. 6 position motorized nosepiece
5. Objective slider for 20× objective with motorized correction collar
6. Nosepiece piezoelectric actuator for a precise control of Z positioning
• Scanner
1. Tandem (conventional and resonant) galvanometer scanhead.
2. Maximum scan format with conventional scanner 8192 × 8192 pixels
3. Scanning speeds in conventional scanning: user adjustable from 1 to 1800 Hz/lines per sec (up to 3600 Hz in bidirectional mode)
4. Scanning speed in bidirectional mode (resonant scanning): 16000 Hz/lines per sec (minimal zoom 1.3×)
• Excitation sources
1. Infrared laser - Ti-Sapphire femtosecond pulsed Chameleon Ultra II (Coherent Inc.) with tuning range 680-1080 nm, 40 nm/se

Technical Capabilities

• Deep tissue imaging of live and fixed specimens with low phototoxicity and photobleaching
• In vivo (mouse) and in vitro (cultured cells, explanted organs) microscopy
• Enhanced resolution confocal and multiphoton microscopy
• 3D volume scanning, time lapse and automated multi-region imaging

CD BioSciences offers you a tissue imaging solution with unparalleled speed and excellent performance and flexibility, designed to provide the perfect research tool for the field of tumor immunology and digital pathology. If you are interested, please do not hesitate to contact us.

For research use only, not intended for any clinical use.

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