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Neuroscience is a multidisciplinary field involving the study of the structure and function of the nervous system. It aims to understand the development of cognitive and behavioral processes, as well as to understand various diseases (such as Alzheimer's or Parkinson's disease) and find treatments for them. Neuroscientists often need to use microscopy to study challenging and complex samples to better understand the nervous system. CD BioSciences offers a comprehensive range of Elekta MAGNETOENCEPHALOGRAPHY (MEG)-based imaging solutions to enable you to overcome these challenges.
METHODS & EXPERTISE FOR RESEARCH INFRASTRUCTURE
A major advantage of this technique is that, unlike the EEG, the magnetic field penetrates the intervening layers (e.g., skull, scalp) without distortion. This usually results in a "cleaner" signal (better SNR) and easier handling of the modeling of basic generators. Thus, in addition to the time-high resolution, a spatial resolution (theoretically ~ 1 mm) satisfactory for many purposes is possible.
The Elekta TRIUX device allows carrying out investigations in which neuronal activity with high temporal resolution (currently up to a maximum of 10kHz) must be derived. This is highly relevant in many neurocognitive as well as clinical questions.
Apart from the consideration of "evoked" brain responses, an exact timing is also necessary to resolve oscillatory activity on different temporal scales. The use of modern inverse methods (normally in combination with a structural MRI) allows conclusions to be drawn on (probable) generators. Togethe
The Core Facility MEG supports all interested parties of the Salzburg neuroscientific community to carry out MEG studies at an international top level.
In addition to the provision of the laboratory, it includes the training of users, consultancy, etc. : a) at the design, b) at the implementation by means of the Psychophysics Toolbox, c) at the testing of the experientalscripts (including triggering and timing) and d) at the evaluation. Concerning the latter the core facility team regularly provides well-maintained and tested fieldtrip-based analysis pipelines.
Magnetoencephalography (MEG) is a neuroscientific technique that can be used to detect brain activity noninvasively with high temporal resolution. Analogously like the EEG, the underlying signal is directly attributable to neuronal activity.
Compared to the EEG, the MEG measures (extremely weak) changes of the magnetic field on the head surface. To achieve this, in addition to a complex magnetic shielding, the use of superconducting sensors (so-called SQUIDs) is necessary. In order to maintain the superconducting state, cooling by means of liquid helium is necessary.
The TRIUX system from Elekta, which is available at the MEG laboratory of the CCNS, has a total of 306 sensors (102 magnetometers and 204 gradiometers) that capture the signal from a total of 102 positions. If required, the deduction can be expanded by 128 EEG electrodes. The sampling rate of the device is up to max.10kHz.
The laboratory is used by CDK mostly clinically (mainly for epilepsy diagnostics) and by researchers
CD BioSciences' solutions can combine high resolution, deep imaging, and large section display to give you the flexibility to image different types of samples such as live cells, tissues, organoids, and model organisms. If this is of interest to you, please contact us directly.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.