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The characterization of molecules is an important part of the process, enabling the physical and chemical properties of molecules to be resolved. CD BioSciences has excellent analytical staff, years of analytical experience, and cutting-edge instrumentation. Using LC-MS, multiple HPLC, and other techniques, we can accurately quantify/characterize the DAR of coupled drugs, residual small molecules, endotoxins, and more.
FEI Tecnai G2 Spirit BioTWIN Specifications
1. Accelerating Voltage: 80 kV nominally
2. Electron Source: LaB6
3. Stage Tilt Range: ± 70°
4. Line Resolution: 0.34 nm
5. Cs Objective: 6.3 mm
6. Specimen Exchange: < 5 minutes
7. Operating Temperature: Room temperature; approx.21 degrees; cryo shield cooled in vacuum with LN2
8. Veleta CCD Camera:
9. Retractable (pneumatic), side mounted (top) peltier cooled, lens coupled CCD camera
1) Sensor size 2048 × 2048 pixels (4 megapixels).
2) Sensor active area 16.67 mm × 16.67 mm
3) Peltier cooled sensor 10℃ @ 25℃ ambient temperature
4) Noise reduction - Correlated double sampling
5) Physical pixel size 7.4 µm2
6) Dynamic Range 14 bit
7) 5 fps @ full resolution
10. Camera acquisition software: EMSIS RADIUS software
General purpose transmission electron microscope. Ideal for screening grids of negatively stained samples or thin sections at room temperature (microscope is not cryo-capable but is operated with a cryo-shield).
Configuration
BioTWIN lens configuration for increased contrast.120kV TEM microscope (operated at 80kV) with a LaB6 filament and an EMSIS Veleta camera (top, side-mounted). The Camera operates using RADIUS software from EMSIS.
CD BioSciences offers its customers FEI Tecnai G2 Spirit TEM-based molecular characterization services that contribute to the process and drug development process of biomolecules. If you need our technical support, please contact us directly.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.