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The characterization of molecules is an important part of the process, enabling the physical and chemical properties of molecules to be resolved. CD BioSciences has excellent analytical staff, years of analytical experience, and cutting-edge instrumentation. Using LC-MS, multiple HPLC, and other techniques, we can accurately quantify/characterize the DAR of coupled drugs, residual small molecules, endotoxins, and more.
The Bio-SANS instrument is dedicated to structural analysis of complex biological systems. It is part of the Center for Structural Molecular Biology (CSMB) at Oak Ridge National Laboratory along with the Bio-Deuteration Laboratory (BDL). The Bio-SANS instrument, with its dual detector system, offers users a wide dynamic Q-range (~300) in a single exposure. Users can avail a variety of sample environments for static and in-operando measurements of biomacromolecules and biomaterials.
Specifications
1. Wavelength: 6 < λ < 25 Å
2. Wavelength resolution: Δλ ⁄ λ = 9-45%
3. Q range: 0.0009-1 Å-1
4. Sample-to-detector distance: 2.25-15.5 m
5. Detector: 2-D linear position-sensitive detector
6. Detector size: Main detector 1 × 1 m²
7. Wide angle detector: 1 × 0.8 m²
8. Detector resolution: Main detector 192 × 256 pixels
9. Wide angle detector: 160 × 256 pixels
10. Max count rate: 1 MHz
1. Biomacromolecules and their assemblies
2. Protein/nucleic acid/lipid complexes
3. Biomembranes
4. Membrane proteins
5. Liposomes
6. Nanodiscs
7. Complex Systems
8. In-Cellulo studies
9. Viruses
10. Biomass & Biofuels
11. Plant cell wall structure & dynamics
12. Biomimetic/Bioinspired Systems
13. Microemulsions
14. Micellar systems
15. Gels & fibers
Bio-SANS was designed and optimized for analysis of the structure and function of complex biological systems.
CD BioSciences offers its customers BIO-SANS-based molecular characterization services that contribute to the process and drug development process of biomolecules. If you need our technical support, please contact us directly.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.