Confocal microscopy is an optical imaging technique that uses point-by-point illumination and spatial pinhole modulation to remove scattered light from the non-focal plane of the sample, allowing for improved optical resolution and visual contrast compared to traditional imaging methods. CD BioSciences, the imaging experts, can provide you with LaVision Ultramicroscope II SPIM-based confocal microscopy imaging services.
After the installation of a gas exhaust system the microscope is now available. The laser lines are 488, 561 and 640 nm.
The Ultramicroscope II is a light sheet microscope that is especially made for big specimen like mice brains. Imaging of such large structures requires optical clearing.
At the moment we have two objectives:
1. LaVision LVMI 4× NA 0.3 objective with a working distance of 6 mm. The refractive index can be adjusted in the range from 1.30 to 1.60.
2. LaVision MI Plan 12× NA 0.53 objectice with a working distance of 10.9 mm. The refractive index can be adjusted from 1.374 to 1.667.
The camera is an Andor Neo sCMOS wit 5.5 Mpixel and a pixel size of 6.5 µm. High resolution images may be acquired by stitching smaller image fields.
Lightsheet microscope for imaging of cleared large specimens (up to 30×30×15 mm) in up to three channels.
CD BioSciences' LaVision Ultramicroscope II SPIM-based confocal microscopy service is an ideal partner for cutting-edge biomedical research, providing precise 3D imaging, as well as accurate imaging of cell structure and dynamic processes, all in one package. If you are interested, please feel free to contact us.
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