High-Throughput Screening Service—Tecan • Spark

High-throughput screening technology is designed to screen a large number of biomodulators against selected targets and is applied to screen different types of libraries such as chemical, genomics, protein, and peptide libraries. CD BioSciences, the industry leader in high-throughput screening services, provides high-quality, customized high-throughput screening services. Services cover both biochemical and cell-based assays.

Name of the Instrument/Platform

Tecan • Spark

Introduction

Detection modes:
• Absorbance
– including UV/vis spectra
• Fluorescence top and bottom
– including spectra
• Time-resolved fluorescence (TRF)
– including spectra
• Fluorescence Resonance Energy
Transfer (FRET)
• Time-resolved fluorescence Resonance Energy Transfer (TR-FRET)
• Fluorescence Polarization (FP)
• Luminescence - glow, flash, multi-color, spectra
• AlphaScreen^®, AlphaLISA^® and AlphaPlex^™

Applications

• ELISAs
• Low-volume DNA/RNA quantification
• Nucleic acid labeling efficiency
• Protein quantification
• Reporter gene assays
• Homogeneous time-resolved fluorescence (HTRF^®)
• Transcreener^®
• Dual-Luciferase^® Reporter (DLR^™)
• Bioluminescence resonance energy transfer (BRET) - including Nano-BRET^™

Summary

The Spark multimode microplate reader offers solutions for virtually any life science research or drug discovery applications. The unique Fusion Optics allows any combination of filters or monochromators on both the excitation AND emission sides for every fluorescence measurement. This is complemented by the unparalleled multi-color luminescence module, which offers flexibility for virtually any luminescence measurement, including flash, glow, BRET and laser-based Alpha Technology. Spark's Te-Cool^™ module allows the user to set the reader temperature at, or even below, ambient for more accurate and robust results.

CD BioSciences' Tecan • Spark-based high-throughput screening solutions are available to meet a wide range of high-throughput experimental needs. We have standard workflows, application expertise, customized designs, comprehensive after-sales service, and extensive technical support resources. If you are interested, please contact us directly.

For research use only, not intended for any clinical use.

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