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Chemical and Biomolecular Analysis Services—Circular Dichroism (CD) Spectroscopy

CD BioSciences' chemical and biomolecular analysis laboratories have a wide range of instruments including high-field nuclear magnetic resonance (NMR), liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS), high-performance liquid chromatography (HPLC) and more. Based on these instruments, we can monitor chemical reactions and protein stability, determine molecular structures, obtain purity (including trace metal content), or study other properties of various materials.

Name of the Instrument/Platform

Circular Dichroism (CD) Spectroscopy

Applications

1. Protein conformational studies
2. Quantitative analysis of pharmaceuticals
3. Formulation studies
4. Protein folding studies
5. DNA/RNA interactions
6. Enzyme kinetics
7. Purity testing of optically active substances
8. Natural products chemistry

Summary

Circular dichroism (CD) spectroscopy is a form of light absorption spectroscopy that measures the difference in absorbance of right- and left-circularly polarized light (rather than the commonly used absorbance of isotropic light) by a substance. The J-1500 Circular Dichroism spectrophotometer in our facility is specifically designed for high sensitivity measurements in the near- and far-UV regions, for scientists that need confidence in the data from characterization studies of biomolecule structure, function and stability under a wide variety of experimental conditions. Temperature control systems can be coupled with multi-position cells to run thermal melts, providing researchers with CD and thermodynamic data sets for conformational and folding studies.

If you are interested in Circular Dichroism (CD) Spectroscopy-based chemical and biomolecular analysis services, please do not hesitate to contact us.

For research use only, not intended for any clinical use.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.

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