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The CD BioSciences biophysical characterisation laboratories are equipped with state-of-the-art instruments for studying proteins, nucleic acids, lipids, and complexes. Researchers can benefit from our Beckman ProteomeLab XL-I Analytical Ultracentrifuge with Fluorescence Detection System-based biophysical characterisation services.
The ProteomeLab XL-A/XL-I is used for in-solution characterization of proteins, oligomers, aggregates, particles, colloids, and small structures. The column-free separation technique of the ProteomeLab XL-A/XL-I measures the relative change in the distribution of molecular weights, providing an efficient way to measure heterogeneity, stoichiometry and self-associating systems. The measurements are based on the first principles of thermodynamics and hydrodynamics, so no standards or calibrations are required.
Sensitive absorbance optics enable analysis of most samples. Interference optics can be used for low concentrations or samples without chromophores. Both systems can be implemented simultaneously, to maximize data acquisition in a single run. There are two different rotor configurations, and a variety of cell types, to enable multiple experimental designs. The wide range of rotational velocities also allow investigators to probe protein size, oligomerization, and binding constants
The ProteomeLab XL-I is used for in-solution characterization of proteins, oligomers, aggregates, particles, colloids, and small structures. The analytical ultracentrifuge in the facility can be used for several types of experiments, but the two most widely used are sedimentation velocity and sedimentation equilibrium.
In the chemistry-biology community, our service is one of the best options for teams working on biophysical characterisation. Do not hesitate to contact us if you are interested in this.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.