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Biomedical Imaging Service—Zeiss ELYRA S1 (SR-SIM) Super Resolution Microscope

Biomedical imaging usually refers to the science of researching image composition, capture and storage technology, and the research and development of instruments and equipment. CD BioSciences has a variety of imaging equipment, which can visually describe and accurately measure the structure and function of living organisms across scales, provide imaging omics research methods for complex life science problems and major diseases, and facilitate panoramic research and analysis of biomedical science.

Name of the Instrument/Platform

Zeiss ELYRA S1 (SR-SIM) Super Resolution Microscope

MANUFACTURER:
Zeiss

Introduction

1. Microscope: The ELYRA S1 system uses a high resolution AXIO Observer Z1 inverted microscope stand with transmitted (HAL), UV (HBO) and laser illumination sources. The scope has 10× (dry), 63× (oil) and 100× (oil) objectives, and a GFP/RFP/Alexa 633 fluorescence filter set for viewing samples.
2. Resolution: The ELYRA S.1 system achieves a lateral resolution of ~ 100 nm and an axial resolution of ~ 200 nm through the use of SR-SIM. This system has the ability to penetrate up to 20 µm into the tissue.
3. Lasers: High power solid-state 405 nm, 488 nm and 561 nm lasers for imaging the blue, green and red standard fluorescent labels.
4. Camera: EM-CCD camera (Andor iXon) provides maximum sensitivity and speed of acquisition.
5. Software: ZEN 2011 software with SIM analysis module.
6. Computer: ELYRA S1 system is controlled via a HP Z820 workstation with the Windows 7 (64 bit) operating system.

Applications

Shorter acquisition times and ability to work with standard fluorophores in standard conditions make this system more flexible and suitable for imaging live and fixed samples. High axial and lateral resolution makes this system optimal for nano research.

Technical Capabilities

Capabilities: This system can acquire multi-color SR-SIM data with up to four channels. It allows collection of super resolved images in 3D by means of Z-stack or optical sections.

Summary

1. High resolution Axio Observer Z1 Inverted Microscope stand
2. Super Resolution System with 3 laser lines (405, 488, 561nm) and ZEN software
3. Ideal for 3D-SIM and live cell imaging of even very small organisms
4. Can produce increased lateral and axial resolution (resolve structures as small as 100 nm)
5. Works with standard fluorochromes, and acquires and processes data very rapidly

CD BioSciences offers you biomedical imaging solutions based on Zeiss ELYRA S1 (SR-SIM) Super Resolution Microscope. We look forward to being your research partner. Please do not hesitate to contact us if you need us.

For research use only, not intended for any clinical use.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.

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