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Biomedical Imaging Service—LaVision BioTec UltraMicroscope II

Biomedical imaging usually refers to the science of researching image composition, capture and storage technology, and the research and development of instruments and equipment. CD BioSciences has a variety of imaging equipment, which can visually describe and accurately measure the structure and function of living organisms across scales, provide imaging omics research methods for complex life science problems and major diseases, and facilitate panoramic research and analysis of biomedical science.

Name of the Instrument/Platform

LaVision BioTec UltraMicroscope II

Introduction

1. UltraMicroscope II: This imaging system utilizes 6 light sheets (3 left, 3 right) to excite samples from the side while the fluorescence light is detected perpendicular to the plane of illumination. Moving the sample through the light sheet generates a 3D image stack. Selective excitation of the focal plane significantly reduces bleaching and photo toxicity. The dynamic horizontal light sheet focus provides excellent Z-resolution.
2. Microscope: Olympus MVX-10 Zoom Body providing magnification steps from 0.63× to 6.3× for the Olympus MVPLAPO 2×C objective. Infinity corrected optics setup used for other LaVision BioTec manufactured objectives.
3. Objectives: The scope has 1.3×, 2×, 4× and 12× objectives.
4. Camera: Andor Neo sCMOS camera.
5. Fluorescence Filters: Standard filter sets for imaging green, red, far-red and infrared fluorophores.
6. Software: ImSpector Pro for imaging and Imaris 9.1 for image processing.
7. Computer: The microscope is controlled via a workstation (A

Applications

This system is good for 3D imaging of large optically cleared and fluorescently labeled samples.

Technical Capabilities

Capabilities: Multi-color imaging of large fixed and cleared organs and entire small animals.

Summary

1. Light Sheet Fluorescence Microscope for Imaging Large Samples
2. Imaging at 488 nm, 561 nm, 640 nm and 785 nm Excitation Wavelengths
3. 1.3×, 2×, 4× and 12× Objective Lenses
4. Six Light Sheets for Homologous Illumination
5. Working distance of up to 10 mm
6. Dynamic Horizontal Focus for Better Z Resolution
7. Imaging in Aqueous Buffers or Organic Solvent Medium

CD BioSciences offers you biomedical imaging solutions based on LaVision BioTec UltraMicroscope II. We look forward to being your research partner. Please do not hesitate to contact us if you need us.

For research use only, not intended for any clinical use.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.

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