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Transmission electron microscopy is an important tool for the observation and study of ultrastructure and is widely used in a variety of disciplines such as histology, cytology, virology, pathology, and materials science, for example, to observe the overall structure of cells, changes in cell membranes, organelles in cell walls, the distribution of materials into cells, autophagic vesicles produced by cells in response to external stimuli, and invasive structures invaded by external organisms. CD BioSciences' Philips CM200 Transmission Electron Microscope-based transmission electron microscopy imaging service enables customers to see the microscopic world.
A transmission electron microscope (TEM) is comparable in design to an inverted light microscope. An electron gun at the top of the column produces a beam of electrons, which are accelerated down the column, and focused into a coherent beam by electromagnetic lenses onto the sample. The specimen, mounted on a small copper grid, must be thin enough to allow the beam to pass through it. The objective lens forms an image of the sample, which is further magnified by the imaging lenses below. The image is projected onto the fluorescent screen at the bottom of the column. In various positions in the column are a series of apertures, which serve to eliminate any stray electrons from the image forming process.
RECOMMENDED SAMPLE SIZE: Grid size is 3 mm diameter, samples should be < 100nm thick. Initial sample fixation for biological samples should not exceed 1 mm3 (prior to sample dehydration & embedding). Contact us for protocols.
RESOLUTION: 0.2 nm
MAGNIFICATION: 2,000,000×
The Philips CM200 TEM is a high resolution Transmission Electron Microscope capable of operating up to 200kV.
Attachments include a full cryo setup with an EDAX EDS system and Gatan 678 Image Filter and P/EELS, and Gatan 832 SC1000 CCD camera, allowing for full imaging and analytical capability. This makes it ideal for high resolution imaging and analysis of nanotechnology samples includingnanoparticles and nanotubes. It is also used routinely for imaging of biological and mineralogical samples.
CD BioSciences' transmission electron microscopy imaging laboratory has the professional equipment and experienced scientists. We are guided by the needs of our customers and are committed to promoting the progress of their research in biology and materials. Please feel free to contact us for any collaboration or questions.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.