Molecular Imaging Service—Perkin Elmer IVIS Spectrum System

CD BioSciences' molecular imaging platform is equipped with state-of-the-art equipment and we are at the forefront of experimental animal imaging applications. We can provide a wide range of experimental animal models for image data acquisition and image data analysis. We can perform quantitative molecular imaging evaluation of animal models of various tumors, heart diseases, vascular diseases, neurodegenerative diseases, bone diseases, and other diseases.

Name of the Instrument/Platform

Perkin Elmer IVIS Spectrum System

MANUFACTURER:

Perkin

Introduction

An optimized set of high efficiency filters and spectral un-mixing algorithms lets you take full advantage of bioluminescent and fluorescent reporters across the blue to near infrared wavelength region. It also offers single-view 3D tomography for both fluorescent and bioluminescent reporters that can be analyzed in an anatomical context using our Digital Mouse Atlas or registered with our multimodality module to other tomographic technologies such as MR, CT or PET.
For advanced fluorescence pre-clinical imaging, the IVIS Spectrum has the capability to use either trans-illumination (from the bottom) or epi-illumination (from the top) to illuminate in vivo fluorescent sources. 3D diffuse fluorescence tomography can be performed to determine source localization and concentration using the combination of structured light and trans illumination fluorescent images. The instrument is equipped with 10 narrow band excitation filters (30 nm bandwidth) and 18 narrow band emission filters

Feature Highlights

1. High-sensitivity in vivo imaging of fluorescence and bioluminescence
2. High throughput (5 mice) with 23 cm field of view
3. High resolution (to 20 microns) with 3.9 cm field of view
4. Twenty-eight high efficiency filters spanning 430-850 nm
5. Supports spectral unmixing applications
6. Ideal for distinguishing multiple bioluminescent and fluorescent reporters
7. Optical switch in the fluorescence illumination path allows reflection-mode or transmission-mode illumination
8. 3D diffuses tomographic reconstruction for both fluorescence and bioluminescence
9. Ability imports and automatically co-register CT or MRI images yielding a functional and anatomical context for your scientific data.
10. NIST traceable absolute calibrations
11. Gas anesthesia inlet and outlet ports
12. Class I Laser Product

Summary

CapabilitiesThe IVIS^® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.

CD BioSciences offers a highly regarded Perkin Elmer IVIS Spectrum System-based molecular imaging service. For more information, please do not hesitate to contact us.

For research use only, not intended for any clinical use.

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