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CD BioSciences' molecular imaging platform is equipped with state-of-the-art equipment and we are at the forefront of experimental animal imaging applications. We can provide a wide range of experimental animal models for image data acquisition and image data analysis. We can perform quantitative molecular imaging evaluation of animal models of various tumors, heart diseases, vascular diseases, neurodegenerative diseases, bone diseases, and other diseases.
FDG for PET imaging is acquired from Cardinal Health, which is next door. There is also a radiopharmacy for development of new probes in both non-cGMP and cGMP environments. Other isotopes (eg. Cu-64, Y-86, Zr-89) can be received from facilities around the country as required.
Technical specifications:
• 7T field strength
• Actively-shielded superconducting wide-bore magnet
• Reduced stray field
• Actively-shielded and water cooled gradients with integrated shim sets up to 2nd order
• Full animal monitoring and heating systems
• Isoflurane vaporizer
12 cm gradients for high resolution MRI of mice and rats
• Outer / inner diameter: 198 mm / 114 mm
• Gradient amplitude: 440 mT/m
• Slew rate: 3440 T/m/s
• Linearity 80 / 50 mm DSV: < ± 4.5%, < ± 1.0%
20 cm gradients for use with PET insert and for rabbit MRI
• Outer / inner diameter: 301.5 mm / 200.5 mm
• Gradient amplitude: 200 mT/m
• Slew rate: 640 T/m/s
• Linearity 130 / 100 mm DSV: < ± 3%, < ± 2%
This is a 7T MRI with an insert for simultaneous acquisition of PET images and is one of a handful of systems installed around the world. In addition to the full capabilities of preclinical MRI, we can perform simultaneous PET imaging with 5 second temporal resolution or 0.7 mm spatial resolution (FDG). We have specialized RF coils for proton imaging of mouse brain and body, rat brain and body, and larger animals up to rabbit size. The system has built-in sequences for anatomical imaging, fMRI, diffusion weighted imaging, CEST and many other applications.
CD BioSciences offers a highly regarded Bruker BioSpec 70/30-based molecular imaging service. For more information, please do not hesitate to contact us.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.