Email:
Tel: 
The characterization of molecules is an important part of the process, enabling the physical and chemical properties of molecules to be resolved. CD BioSciences has excellent analytical staff, years of analytical experience, and cutting-edge instrumentation. Using LC-MS, multiple HPLC, and other techniques, we can accurately quantify/characterize the DAR of coupled drugs, residual small molecules, endotoxins, and more.
METHODS & EXPERTISE FOR RESEARCH INFRASTRUCTURE
The X-ray diffractometer is the instrumental centerpiece for the molecular structure elucidation. The present device is designed especially for the elucidation of biologically relevant macromolecules such as proteins and DNA. The structure elucidation is the key for the mechanistic understanding of these molecules. Specific applications include proteins with relevance in the fields of immunology, allergy, antigen processing, pathogen-host interaction, blood clotting and others. All these examined proteins play a significant role in health related topics. The structure determinations achieved in this way have already opened up new possibilities for development in the diagnosis and therapy of the respective disease areas.
X-ray structure analysis of macromolecules (mainly proteins and DNA)
The x-ray diffractometer consists of an x-ray generator, x-ray optics (mirror system), a Cryo system and an x-ray area counter. The x-ray generator produces x-ray radiation by means of a copper rotary anode (Cu Kα, 1.54 Å), which is further focused and monochromatized through a mirror system.
The nitrogen powered Cryo system allows a temperature control in the temperature window from 80 to 300 kelvin to a degree. The imaging plate technology of the x-ray detector allows a detection of x-ray diffraction with extremely long cell axes of up to 500 Å and a resolution of better than 1.5 Å.
CD BioSciences offers its customers Microstar HF Microfocus Rotating Anode-based molecular characterization services that contribute to the process and drug development process of biomolecules. If you need our technical support, please contact us directly.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.