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The characterization of molecules is an important part of the process, enabling the physical and chemical properties of molecules to be resolved. CD BioSciences has excellent analytical staff, years of analytical experience, and cutting-edge instrumentation. Using LC-MS, multiple HPLC, and other techniques, we can accurately quantify/characterize the DAR of coupled drugs, residual small molecules, endotoxins, and more.
The sample must be cleared of any air bubbles and dust particles; the minimum sample volume is 50μL.
In general, light scattering experiments can be successfully applied to molecular masses of 10,000 Da or greater. Smaller molecules usually require higher concentrations than bigger particles, in order to reach a sufficient intensity of scattered light. As a rule of thumb for molecules of a molecular weight of approximately 50,000, a sample concentration of 1 mg/mL is a good starting point.
This batch mode DLS features a Brookhaven BI-200 goniometer and BI-9000 high speed correlator and a 3 watt argon-ion laser operating at 514 nm.
CD BioSciences offers its customers Dynamic Light Scattering-based molecular characterization services that contribute to the process and drug development process of biomolecules. If you need our technical support, please contact us directly.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.