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Confocal microscopy is an optical imaging technique that uses point-by-point illumination and spatial pinhole modulation to remove scattered light from the non-focal plane of the sample, allowing for improved optical resolution and visual contrast compared to traditional imaging methods. CD BioSciences, the imaging experts, can provide you with Lattice Light-Sheet Microscope-based confocal microscopy imaging services.
Cell imaging, tissue imaging (max size ~ 1 mm3), live imaging, time-lapse, 3D dynamics
• Designation
Lattice Light Sheet miroscope
• Light Source
Laser combiner : 405 nm (300 mW), 488 nm (1 W), 560 nm (2 W), 642 nm (2 W)
• Objectives
Excitation : Special Optics 0.65 NA, 3 mm WD, water dipping Detection : Nikon 25×, 1.1 NA, 2 mm WD, water dipping Inverted widefield fluorescence : Olympus 40×, 0.8 NA
• Light Sheet Dimensions
0.5 µm thick by 15 µm long and 100 µm large (can be modified)
• XYZ Resolution
270 nm × 270 nm × 550 nm (@ 488 nm)
• Camera
Hamamatsu Orca Flash4 v2 sCMOS, pixel size 6.5 µm
• Sample Mounting
Sample mounted on 5 mm diameter glass coverslips
• Photomanipulation Module
Photomanipulation (FRAP, uncaging, photoactivation,...) at 405, 488, 560 or 642 nm targeted to user-defined ROIs via a pair of galvo-mirrors
• Link
A lattice light-sheet microscope (LLSM) at BIC - 30 Nov 2018
• Link
High resolution 3D imaging in brain slice with LLS
• Category
Photonic imaging
CD BioSciences' Lattice Light-Sheet Microscope-based confocal microscopy service is an ideal partner for cutting-edge biomedical research, providing precise 3D imaging, as well as accurate imaging of cell structure and dynamic processes, all in one package. If you are interested, please feel free to contact us.
Please fill out the form below and we will get back to you as soon as possible with a quotation for the item you are interested in.
CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.