Enhanced Neuroimaging Service—LaVision Ultramicroscope II Light Sheet Microscope

CD BioSciences' Neuroimaging Centre is a research platform with multiple large research facilities at its core, providing enhanced neuroimaging services in multiple areas. We offer LaVision Ultramicroscope II Light Sheet Microscope-based neuroimaging solutions, please read on to find out more.

Name of the Instrument/Platform

LaVision Ultramicroscope II Light Sheet Microscope

Introduction

Detailed Specifications
1. Multiple Laser Lines
405 nm (≥100mW)
488 nm (≥100mW)
561 nm (≥100mW)
640 nm (≥100mW)
2. Objectives
Olympus MVPLAPO 2×/ 0.5
WD
20 mm without dipping cap
6 mm with short dipping cap
4 mm with long dipping cap
3. Lavision BioTec LVMI-Fluor 4×/0.3 (refractive index corrected)
WD
5. 6-6.0 mm
4. Camera
Andor Neo (pixel calibration)
Intel i7 3.60 GHz processor (4 cores, w/ HT), 32GB RAM, and 2GB NVIDIA Quadro K420
Optical Elements
1. Scanhead
Protocols-In Development
2. Image Handling / Processing
3. Multi-Channel Acquistion
4. Optimizing Rayleigh width with horizontal scanning
5. Tiling

Feature Highlights

1. Imaging in aqueous buffers and organic solvents
2. Optical zoom from 1.26× to 12.6×
3. Large sample uptake up to 30 mm × 30 mm × 15 mm-Acquisition time in ~ 30 minutes for single channel
4. Dynamic horizontal focusing for better Z resolution
5. 6 light sheets for homogenous illumination
6. Large field of view with a diagonal of 17.6 mm

Summary

The LaVision light sheet UltraMicroscopes allow users to image cleared tissue in either aqueous buffers or organic solvents.

CD BioSciences provides LaVision Ultramicroscope II Light Sheet Microscope-based neuroimaging solutions to customers worldwide to help resolve the mechanisms of neurological diseases. If you are interested, please contact us directly.

For research use only, not intended for any clinical use.

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