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CD BioSciences' Neuroimaging Centre is a research platform with multiple large research facilities at its core, providing enhanced neuroimaging services in multiple areas. We offer Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO)-based neuroimaging solutions, please read on to find out more.
The AOSLO system combines a 3-channel scanning laser ophthalmoscope system (SLO) with an additional channel for adaptive optics (AO) technology. The system provides the ability to image, stimulate, and identify individual photoreceptors in the intact human eye. The system is also confocal, allowing the imaging of additional retinal elements at different retinal depths as the focal plane is adjusted. The system utilizes a super-continuum laser source to provide source light at multiple wavelengths (currently 543, 680, 830, 940 nm). The SLO portion of the system uses a system of lenses and mirrors to produce a tiny beam that is scanned across the retina. The small amount of light reflected from the eye is confocally imaged on pinholes at the entrance of three detectors (photomultiplier tubes), one for each wavelength. The changes in intensity of light at the detector over time is computed for each position of the scanning mirrors and video images are reconstructed from these data. The ma
Adaptive optics is a technology developed for astronomic imaging but also currently used to image the retina of the eye. Traditional optics are not effective at resolving the image at the scale needed, as optical aberrations blur the image. AO solves this by combining a device that measures the aberrations with a mirror that deforms in shape to correct for optical aberrations. In doing so, it returns a clear image of the retina. It can be used for both research and ophthalmological diagnosis of clinical conditions.
CD BioSciences provides Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO)-based neuroimaging solutions to customers worldwide to help resolve the mechanisms of neurological diseases. If you are interested, please contact us directly.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.