Biological Imaging Service—Zeiss LSM 880 Airyscan Fast Live Cell

Biological imaging is an important research tool for understanding tissue structure and elucidating the various physiological functions of living organisms. It uses light or electron microscopy to obtain direct images of the microstructure of biological cells and tissues, and the resulting images are analyzed to understand the various physiological processes of biological cells. CD BioSciences' Bioimaging Centre has dozens of devices and, more importantly, our expertise and experience are invaluable to the industries and clients we serve. We can provide Zeiss LSM 880 Airyscan Fast Live Cell-based bioimaging services.

Name of the Instrument/Platform

Zeiss LSM 880 Airyscan Fast Live Cell

MANUFACTURER:

Zeiss

Introduction

Laser Lines
1. Argon: 458, 488, 514 nm
2. Diode: 405 nm
3. DPSS: 561 nm
4. HeNe: 633 nm.
Objectives
1. EC Plan Neofluor 10×/0.3 NA
2. Plan Apo 20×/0.8
3. Plan Apo 40×/1.2 NA Water or Type W Oil
4. Plan Apo 63×/1.4 NA Oil DIC

Feature Highlights

1. Airyscan to achieve 1.7× resolution (140 nm XY, 400 nm Z) and 4-8× sensitivity
2. FAST model for 4× speed up to 100fps
3. Axio Observer inverted platform with motorized XYZ stage
4. Definite focus 2 prevent focus drift over time
5. Piezo with 500um travel range for extremely fast Z stacks
6. Tokai-Hit stagetop incubation chamber
7. Zen Black software with the modules of Z stacks, timelapse, tiling, multi position, co localization, FRAP, super resolution, deconvoltuion, 3D processing.

Applications

1. Super resolution confocal imaging of fixed or live samples, photoactivation, or photoconversion in live cells or organisms
2. Capturing fast events such as Ca²⁺ imaging
3. FRAP
4. FRET

Summary

LSM 880 Airyscan Fast Live Cell is a unique confocal that provides high resolution, sensitivity and speed that enables gentle live cell imaging with super resolution. Airyscan delivers super resolution of 140 nm XY, and 4-8 times sensitivity. The FAST module increases speed 4 times up to 100 fps, which increase productivity when performing quantitative imaging. Temperature, CO₂, humidity controlled incubator is optimized for time lapsing live imaging.

In recent years, with the development of optical imaging technology, especially the introduction of digital imaging and computer image analysis, bioimaging has become an indispensable method in cell biology research. CD BioSciences' bioimaging laboratory is committed to providing state-of-the-art technical support to our customers. If you are interested, please do not hesitate to contact us.

For research use only, not intended for any clinical use.

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