Animal Imaging Service—PerkinElmer IVIS Spectrum Fluorescence and Bioluminescence Imaging System

CD BioSciences' animal imaging technology platform has multiple state-of-the-art instruments to study cardiovascular function, skeletal morphology, metabolism, and more by performing ultrasound and computed tomography imaging on live animals. Our PerkinElmer IVIS Spectrum Fluorescence and Bioluminescence Imaging System-based animal imaging service is the right choice for you.

Name of the Instrument/Platform

PerkinElmer IVIS Spectrum Fluorescence and Bioluminescence Imaging System

MANUFACTURER:

Perkin

Feature Highlights

1. High-sensitivity in vivo imaging of fluorescence and bioluminescence
2. High throughput (5 mice) with 23 cm field of view
3. High resolution (to 20 microns) with 3.9 cm field of view
4. Twenty eight high efficiency filters spanning 430 - 850 nm
5. Supports spectral unmixing applications which is ideal for distinguishing multiple bioluminescent and fluorescent reporters
6. Optical switch in the fluorescence illumination path allows reflection-mode or transmission-mode illumination
7. 3D diffuse tomographic reconstruction for both fluorescence and bioluminescence
8. Ability import and automatically co-register CT or MRI images yielding a functional and anatomical context
9. NIST traceable absolute calibrations
10. Gas anesthesia inlet and outlet ports.
11. Both mouse and rat platforms designed to maintain body temperature during anesthesia
12. Compact isoflurane anesthesiology system with an oxygen regulator and flow meter

Applications

Useful in a wide range of biomedical applications including oncology, cardiovascular diseases, stem cell biology, neurobiology, inflammation, toxicology and drug metabolism

Summary

The IVIS Spectrum is the newest instrument in the IVIS line of products and performs bioluminescent and epi- and trans- illumination fluorescent imaging. Unique to the IVIS Spectrum in this line of instruments is the capability to sensitively image both bioluminescent and fluorescent reporters within the same animal and to provide a spectral fingerprint of the signal produced. This is an important advance in in vivo imaging technology as it allows separation of autofluorescence from the emitted signal improving signal resolution. To obtain the spectral fingerprint the Spectrum uses a series of high efficiency narrow band-pass filters coupled with spectral unmixing algorithms to differentiate between multiple shallow and deep fluorescent sources. This provides a mechanism to optimally perform the wide array of fluorescence/bioluminescence research applications of our investigators. The system is also capable of performing 3D tomographic reconstructions for both bioluminescence a

If you need to perform imaging studies on animals such as mice, please contact us directly for details.

For research use only, not intended for any clinical use.

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