CD BioSciences' animal imaging technology platform has multiple state-of-the-art instruments to study cardiovascular function, skeletal morphology, metabolism, and more by performing ultrasound and computed tomography imaging on live animals. Our 3i VIVO™ Microscope-based animal imaging service is the right choice for you.
Light Sources
1. Spinning Disk confocal
1) Imaging Lasers: 488 nm, 561 nm, 640 nm
2) Ablation Laser:532
2. Widefield Fluorescence
3. Xenon Arc 300 Watt 340-700: Lambda DG4
Filters
Widefield Excitation Filters
1. BP 397-409
2. BP 480-500
3. BP 541-569
4. BP 625-645
• Intravital Imaging:
Intravital imaging is the observation of biological processes in living animals/tissue. It introduces new challenges such as achieving higher penetration depths, and dealing with sample mobility. Appreciating that how cells respond in tissue culture has often been shown to be largely different from their response in their true environment makes intravital imaging a crucial step in understanding biological systems.
• Spinning Disk Confocal:
Spinning disk uses the confocal pinhole principle to optically section fluorescently labelled samples by rejecting out of focus light, preventing it from reaching the detector. It is faster than conventional confocal imaging by scanning several points simultaneously, making it well suited for capturing highly dynamic processes in thick specimens.
The 3i VIVO microscope is ideally suited for intravital imaging. Its large stable stage can easily accommodate sizable tissue samples along with clamps and manipulators to aid stabilization. Equipped with a spinning disk unit for high speed optical sectioning, paired with an image intensifier, this system can achieve very high frame rates making the most of every photon. Additionally, a pulsed 532nm ablation laser is available for targeted tissue damage.
If you need to perform imaging studies on animals such as mice, please contact us directly for details.
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CD BioSciences is committed to providing a tailored service to researchers working in the fields of biology and chemistry. Our mission is to accelerate the progress of your research through our technical support.